Highlights

Highlights e pubblicazioni rilevanti

Il collegio dei docenti del Dottorato di Ricerca in Scienze e Tecnologie Biomediche STB) è attivo su linee di ricerca di base e applicata, molte delle  quali riguardano temi strategici individuati dal Link identifier #identifier__6150-1Link identifier #identifier__199599-1Programma Nazionale della Ricerca.

Qui di seguito una selezione di risultati di rilievo ottenuti negli ultimi anni.

Link identifier #identifier__13620-2Farmacologia

• Link identifier #identifier__1383-2Link identifier #identifier__123209-3http://www.uniroma3.it/articoli/pre-prestigioso-finanziamento-della-autism-speaks-al-laboratorio-della-prof-ssa-trezza-12967/
• Link identifier #identifier__152595-2Link identifier #identifier__79731-4http://www.corriere.it/salute/neuroscienze/16_giugno_24/giocare-bisogno-primario-come-mangiare-14aecd42-39fc-11e6-b0cd-400401d1dfdf.shtml

Link identifier #identifier__159780-5Fisiologia

• Link identifier #identifier__94926-4Link identifier #identifier__4352-6https://www.ncbi.nlm.nih.gov/pubmed/28760601
• Link identifier #identifier__80996-2Link identifier #identifier__138643-7https://www.ncbi.nlm.nih.gov/pubmed/30341891

Link identifier #identifier__66286-8Patologia

Link identifier #identifier__6833-9Biotecnologie dei microrganismi

• Link identifier #identifier__141312-8Link identifier #identifier__98961-10D’Angelo F, Baldelli V, Halliday N, Pantalone P, Polticelli F, Fiscarelli E, Williams P, Visca P, Leoni L, Rampioni G (2018) Identification of FDA-approved drugs as antivirulence agents targeting the pqs quorum-sensing system of Pseudomonas aeruginosa. Antimicrob Agents Chemother 62(11). pii:e01296-18.
  
• Link identifier #identifier__190159-11Rampioni G, Ramachandran Pillai C, Longo F, Bondì R, Baldelli V, Messina M, Imperi F, Visca P, Leoni L (2017) Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence. Sci Rep 7(1):11392. Link identifier #identifier__20130-2

Link identifier #identifier__116191-12Microbiologia molecolare e patogenesi microbica

• Link identifier #identifier__125764-9Runci F, Gentile V, Frangipani E, Rampioni G, Leoni L, Lucidi M, Visaggio D, Harris G, Chen W, Stahl J, Averhoff B, Visca P (2019) Contribution of active iron uptake to Acinetobacter baumannii Infect Immun 87(4). pii:e00755-18. Link identifier #identifier__21050-1Link identifier #identifier__189361-13http://dx.doi.org/10.1128/IAI.00755-18
• Lo Sciuto A, Imperi F (2018) Aminoarabinosylation of lipid A is critical for the development of colistin resistance in Pseudomonas aeruginosa. Antimicrob Agents Chemother 62(3). pii:e01820-17. Link identifier #identifier__107989-2Link identifier #identifier__47173-14http://dx.doi.org/10.1128/AAC.01820-17

Link identifier #identifier__38118-15Sicurezza microbiologica degli alimenti e dispositivi diagnostici

• Link identifier #identifier__156251-11Link identifier #identifier__88718-16Antonini G, Stalio O, Arienzo A, Losito F, Murgia L, Angelini MC, Pizzato C, Ricciardi Tenore C, Fiori F (2018) How to warrant microbiological food safety in food companies: problems and a possible solution. Food studies: an interdisciplinary journal 8:29-51. https://doi.org/10.18848/2160-1933/CGP/v08i04/29-51Link identifier #identifier__103063-1
• Arienzo A, Cellitti V, Ferrante V, Losito F, Stalio O, Cristofano F, Marino R, Magrini L, Santino I, Mari A, Visca P, Di Somma S, Antonini G on behalf of GREAT Network (2016) A pilot clinical trial on a new point-of-care test for the diagnosis and fast management of urinary tract infections in the Emergency Department. Int J Clin Med Microbiol 1:107. Link identifier #identifier__155900-2Link identifier #identifier__161260-17https://doi.org/10.15344/2456-4028/2016/107

Link identifier #identifier__45056-18Virologia molecolare e immunità antimicrobica

• Link identifier #identifier__37076-12Link identifier #identifier__84884-19Arenaccio C, Chiozzini C, Columba-Cabezas S, Manfredi F, Affabris E, Baur A, Federico M (2014) Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism. J Virol 88:11529-11539. Link identifier #identifier__43691-1
• Link identifier #identifier__177986-20Percario ZA, Ali M, Mangino G, Affabris E (2015) Nef, the shuttling molecular adaptor of HIV, influences the cytokine network. Cytokine Growth Factor Rev 26:159-173. Link identifier #identifier__166664-2

Link identifier #identifier__69499-21Biologia Teorica e Bioinformatica

• Macari et al. Fragment-Based Ligand-Protein Contact Statistics: Application to Docking Simulations. Int J Mol Sci. 2019;20(10): E2499.
• Toti et al. LIBRA-WA: a web application for ligand binding site detection and protein function recognition. Bioinformatics. 2018;34(5):878-880.
• Brandi et al. A comprehensive in silico analysis of huntingtin and its interactome. J Biomol Struct Dyn. 2018;36(12):3155-3171.
• Di Muzio et al. DockingApp: a user friendly interface for facilitated docking simulations with AutoDock Vina. J Comput Aided Mol Des. 2017;31(2):213-218.

Link identifier #identifier__192325-22Biochimica

• di Masi A, Leboffe L, Polticelli F, et al. Human Serum Albumin Is an Essential Component of the Host Defense Mechanism Against Clostridium difficile Intoxication. J Infect Dis. 2018 Sep 22;218(9):1424-1435.
• Pennisi R, Antoccia A, Leone S, Ascenzi P, di Masi A. Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks. FEBS J. 2017 Aug; 284(15):2378-2395 – Selected as Editor Choice FEBS.