Prof.ssa ELISABETTA AFFABRIS
Qualifica | Professore Ordinario |
Settore Scientifico Disciplinare | BIOS-15/A |
Telefono | 0657336341 |
Cellulare aziendale | 87672 |
elisabetta.affabris@uniroma3.it | |
Indirizzo | Viale Guglielmo Marconi 446 |
Struttura/Afferenza |
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Altre informazioni | Sito web personale Curriculum |
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Ricevimento e materiale didattico
Per telefonare da un edificio dell'Ateneo all'altro SE il numero unico inizia con "06 5733xxxx" basta comporre le ultime quattro cifre del numero esteso.
Contributo in Rivista
- SARS-CoV-2 Evasion of the Interferon System: Can We Restore Its Effectiveness?, SACCHI, ALESSANDRA; GIANNESSI, FLAVIA; SABATINI, ANDREA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2023Link identifier #identifier_person_33669-1 Dettaglio
- Extranuclear effects of thyroid hormones and analogs during development: An old mechanism with emerging roles, INCERPI, SANDRA; GIONFRA, FABIO; CANDELOTTI, ELENA; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; ROSSI, MIRIAM; CARUSO, FRANCESCO SAVERIO; AFFABRIS, ELISABETTA, , 2022Link identifier #identifier_person_101620-2 Dettaglio
- HIV‐1 Nef Protein Affects Cytokine and Extracellular Vesicles Production in the GEN2.2 Plasmacytoid Dendritic Cell Line, AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; ARENACCIO, CLAUDIA; LEONE, STEFANO; AFFABRIS, ELISABETTA, , 2022Link identifier #identifier_person_59586-3 Dettaglio
- Inhibition by Thyroid Hormones of Cell Migration Activated by IGF-1 and MCP-1 in THP-1 Monocytes: Focus on Signal Transduction Events Proximal to Integrin αvβ3, CANDELOTTI, ELENA; MAIOLO, MARIANGELA; GIONFRA, FABIO; PERCARIO, ZULEMA ANTONIA; POLTICELLI, FABIO; PERSICHINI, TIZIANA; COLASANTI, MARCO; AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2021Link identifier #identifier_person_194772-4 Dettaglio
- Thyroid Hormones Interaction With Immune Response, Inflammation and Non-thyroidal Illness Syndrome, GIONFRA, FABIO; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2021Link identifier #identifier_person_187189-5 Dettaglio
- Virus-induced tumorigenesis and IFN system, MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2021Link identifier #identifier_person_95133-6 Dettaglio
- An emerging interplay between extracellular vesicles and cytokines, AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2020Link identifier #identifier_person_25680-7 Dettaglio
- Introduction to the special issue: Extracellular vesicles and biological signal delivery in the inflammatory microenvironment, AFFABRIS, ELISABETTA; MANGINO, GIORGIO, , 2020Link identifier #identifier_person_190135-8 Dettaglio
- The role of extracellular vesicles as allies of HIV, HCV and SARS viruses, GIANNESSI, FLAVIA; AIELLO, ALESSANDRA; FRANCHI, FRANCESCA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2020Link identifier #identifier_person_187558-9 Dettaglio
- Purification and Characterization of Antibodies in Single-Chain Format against the E6 Oncoprotein of Human Papillomavirus Type 16, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2018Link identifier #identifier_person_89617-10 Dettaglio
- The involvement of plasmacytoid cells in HIV infection and pathogenesis., AIELLO, ALESSANDRA; GIANNESSI, FLAVIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2018Link identifier #identifier_person_164000-11 Dettaglio
- Staphylococcus aureus esx factors control human dendritic cell functions conditioning Th1/Th17 response, CRUCIANI, MELANIA; PERCARIO, ZULEMA ANTONIA; RIZZO, FABIANA; BRANDI, VALENTINA; POLTICELLI, FABIO; AFFABRIS, ELISABETTA, , 2017Link identifier #identifier_person_7353-12 Dettaglio
- A novel intracellular antibody against the E6 oncoprotein impairs growth of human papillomavirus 16-positive tumor cells in mouse models, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2016Link identifier #identifier_person_78968-13 Dettaglio
- HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity, MANGINO, GIORGIO; FAMIGLIETTI, MARYLINDA; CAPONE, CATERINA; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; PERSICHINI, TIZIANA; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_119574-14 Dettaglio
- Nef, the shuttling molecular adaptor of HIV, influences the cytokine network, PERCARIO, ZULEMA ANTONIA; ALI, MUHAMMAD; MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_155250-15 Dettaglio
- Role of the microenvironment in tumourigenesis: focus on virus-induced tumors, MANGINO, GIORGIO; AFFABRIS, ELISABETTA, , 2015Link identifier #identifier_person_21923-16 Dettaglio
- Exosomes from human immunodeficiency virus type 1 (HIV-1)-infected cells license quiescent CD4+ T lymphocytes to replicate HIV-1 through a Nef- and ADAM17-dependent mechanism., ARENACCIO, CLAUDIA; AFFABRIS, ELISABETTA, , 2014Link identifier #identifier_person_80993-17 Dettaglio
- In vivo antitumor effect of an intracellular single-chain antibody fragment against the E7 oncoprotein of human papillomavirus 16., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2014Link identifier #identifier_person_149977-18 Dettaglio
- Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release., INCERPI, SANDRA; AFFABRIS, ELISABETTA, , 2013Link identifier #identifier_person_48849-19 Dettaglio
- Cancer Regulator MicroRNA: Potential Relevance in Diagnosis, Prognosis and Treatment of Cancer., MANGINO, GIORGIO; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_46581-20 Dettaglio
- Exogenous Nef Induces Proinflammatory SignalingEvents in Murine Macrophages, MANGINO, GIORGIO; SERRA, VALERIA; PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_60021-21 Dettaglio
- Interferon-β Induces Cellular Senescence in Cutaneous Human Papilloma Virus-Transformed Human Keratinocytes by Affecting p53 Transactivating Activity., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2012Link identifier #identifier_person_113094-22 Dettaglio
- Nongenomic effects of thyroid hormones on the immune system cells: new targets, old players, AFFABRIS, ELISABETTA; INCERPI, SANDRA, , 2012Link identifier #identifier_person_48540-23 Dettaglio
- HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2, PERCARIO, ZULEMA ANTONIA; ACCONCIA, FILIPPO; CHIARABELLI, CRISTIANO; LEONE, STEFANO; NOTO, ALESSIA; POLTICELLI, FABIO; AFFABRIS, ELISABETTA, , 2011Link identifier #identifier_person_177031-24 Dettaglio
- HMGB1 and cord blood: its role as immuno-adjuvant factor in innate immunity, PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2011Link identifier #identifier_person_175448-25 Dettaglio
- The conserved acidic cluster domain of HIV-1 Nef is required to induces a proinflammatory state in primary macrophages: involvement of TNF alpha Receptor Associated Factor 2, CHIARABELLI, CRISTIANO, , 2011Link identifier #identifier_person_63183-26 Dettaglio
- Astrocytes contacting HIV-1-infected macrophages increase the release of CCL2 in response to the HIV-1-dependent enhancement of membrane-associated TNFalpha in macrophages, AFFABRIS, ELISABETTA, , 2010Link identifier #identifier_person_155696-27 Dettaglio
- Immunomodulatory activity of a plant extract containing human papillomavirus 16-E7 protein in human monocyte-derived dendritic cells, AFFABRIS, ELISABETTA, , 2009Link identifier #identifier_person_145062-28 Dettaglio
- Senescence and cell death pathways and their role in cancer therapeutic outcome, AFFABRIS, ELISABETTA, , 2009Link identifier #identifier_person_30306-29 Dettaglio
- In vitro treatment of human monocyte/macrophages with myristoylated recombinant Nef of HIV 1 leads to the activation of Mitogen-Activated Protein Kinases, IkB kinases and Interferon Regulatory Factor 3 and to the release of beta Interferon, AFFABRIS, ELISABETTA, , 2007Link identifier #identifier_person_159241-30 Dettaglio
- Perspectives in biomolecular therapeutic intervention in cancer: from the early to the new strategies with type I interferons, AFFABRIS, ELISABETTA, , 2007Link identifier #identifier_person_46294-31 Dettaglio
- TNF-related apoptosis-inducing ligand (TRAIL) as a pro-apoptotic signal transducer with cancer therapeutic potential., PERCARIO, ZULEMA ANTONIA; AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_63522-32 Dettaglio
- TRAIL as a pro-apoptotic signal transducer with cancer therapeutic potential, AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_48725-33 Dettaglio
- TRAIL is a key target in S-phase slowing-dependent apoptosis induced by Interferon-beta in cervical carcinoma cells, AFFABRIS, ELISABETTA, , 2005Link identifier #identifier_person_187323-34 Dettaglio
- HIV-1 Nef Activates STAT3 in Primary Human Monocyte/Macrophages through the Release of Soluble Factors: Involvement of Nef Domains Interacting with the Cell Endocytotic Machinery, AFFABRIS, ELISABETTA, , 2003Link identifier #identifier_person_199856-35 Dettaglio
- HIV-1 Nef Induces the Release of Inflammatory Factors from Human Monocyte/Macrophages: Involvement of Nef Endocytotic Signals and NF-kB Activation, AFFABRIS, ELISABETTA, , 2003Link identifier #identifier_person_91550-36 Dettaglio
- Review:IRF-1 as a negative regulator of cell proliferation, AFFABRIS, ELISABETTA, , 2002Link identifier #identifier_person_11694-37 Dettaglio
- HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors, AFFABRIS, ELISABETTA, , 2001Link identifier #identifier_person_137232-38 Dettaglio
- Interferon beta induces S-phase slowing via up-regulated expression of PML in squamous carcinoma cells, AFFABRIS, ELISABETTA, , 2000Link identifier #identifier_person_55593-39 Dettaglio
- Retinoic acid is able to induce IRF-1 in squamous carcinoma cells via a STAT-1 independent signalling pathway, AFFABRIS, ELISABETTA, , 1999Link identifier #identifier_person_49074-40 Dettaglio
- Antiproliferative activity of interferon alfa and retinoic acid in SiHa carcinoma cells: the role of cell adhesion, AFFABRIS, ELISABETTA, , 1998Link identifier #identifier_person_192273-41 Dettaglio
- Apoptosis and growth inhibition of squamous carcinoma cells treated with IFN-alfa, IFN-beta and retinoic acid are associated with induction of the cyclin-dependent kinase inhibitor p21, AFFABRIS, ELISABETTA, , 1998Link identifier #identifier_person_115405-42 Dettaglio
- Retinoic acid and interferon inhibition of cell proliferation is associated with apoptosis in squamous carcinoma cell lines. Role of IRF-1 and TGAseII-dependent pathways, AFFABRIS, ELISABETTA, , 1997Link identifier #identifier_person_144579-43 Dettaglio
- Perspectives in interferon and cytokine research., AFFABRIS, ELISABETTA, , 1996Link identifier #identifier_person_185504-44 Dettaglio
- Hemin inhibits the interferon beta-induced antiviral state in established cell lines, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_150052-45 Dettaglio
- IFN-alpha2b and retinoic acid combined treatment affects proliferation and gene expression of human cervical carcinoma cells, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_188517-46 Dettaglio
- Inhibition of protein phosphorylation blocks interferon-induced gene expression and modulates expression of the JAK family protein tyrosine kinases, AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_61150-47 Dettaglio
- Staurosporine inhibits interferon alpha-induced gene expression in Friend erythroleukemia cells through a PKC independent pathway., AFFABRIS, ELISABETTA, , 1995Link identifier #identifier_person_190560-48 Dettaglio
- ACUTE REJECTION OF INTERFERON-TREATED LEUKEMIA-CELLS INJECTED INTO LETHALLY IRRADIATED SYNGENEIC MICE, AFFABRIS, ELISABETTA, , 1993Link identifier #identifier_person_45417-49 Dettaglio
- Friend virus-induced erythroleukemia: a model system to study erythroid differentiation and leukemia development, AFFABRIS, ELISABETTA, , 1993Link identifier #identifier_person_78076-50 Dettaglio
- Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin, AFFABRIS, ELISABETTA, , 1992Link identifier #identifier_person_126327-51 Dettaglio
- TRANSCRIPTIONAL INDUCTION OF H2 (CLASS-I) ANTIGENS AND BETA-2 MICROGLOBULIN BY INTERFERON-GAMMA IN INTERFERON-SENSITIVE AND INTERFERON-RESISTANT FRIEND-LEUKEMIA CELLS, AFFABRIS, ELISABETTA, , 1992Link identifier #identifier_person_109919-52 Dettaglio
- Intracellular heme coordinately modulates globin chains synthesis, transferrin receptor number and ferritin content in differentiating Friend erythroleukemia cells, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_80920-53 Dettaglio
- Positive modulation of hemoglobin, heme and transferrin receptor synthesis by murine interferons-alpha and -beta in differentiating Friend cells: pivotal role of heme synthesis, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_25079-54 Dettaglio
- Post-transcriptional regulation of interferon-beta expression in erythroid Friend cells treated with interferon-gamma, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_194064-55 Dettaglio
- Protein binding to the interferon response enhancer correlates with interferon-induction of 2-5A synthetase in normal and interferon-resistant Friend cells, AFFABRIS, ELISABETTA, , 1991Link identifier #identifier_person_33325-56 Dettaglio
- A full-lenght murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication, AFFABRIS, ELISABETTA, , 1990Link identifier #identifier_person_161959-57 Dettaglio
- Spectrum of biological activity of IFNs. In: "Lymphokines and interferons: from molecular biology to clinical trials", AFFABRIS, ELISABETTA, , 1990Link identifier #identifier_person_48500-58 Dettaglio
- Interferons and differentiation of Friend cells, AFFABRIS, ELISABETTA, , 1989Link identifier #identifier_person_184430-59 Dettaglio
- Poly (ADP-ribose) polymerase activity is inhibited by 2'-5'-oligoadenylates in mouse L-cells, AFFABRIS, ELISABETTA, , 1989Link identifier #identifier_person_135737-60 Dettaglio
- Interferons and oncogenes in the control of cell growth and differentiation: working hypothesis and experimental facts, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_86532-61 Dettaglio
- Interferons-alpha,beta and gamma-resistant Friend cell variants exhibiting receptor sites for Interferons but no induction of 2-5A synthetase and 67K protein kinase, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_82223-62 Dettaglio
- MONOCLONAL-ANTIBODIES ANTI-MURINE INTERFERON (IFN) BETA-NEUTRALIZE THE STIMULATION OF ERYTHROID-DIFFERENTIATION INDUCED BY TREATMENT OF FRIEND-CELLS WITH DIMETHYLSULFOXIDE AND MURINE FIBROBLAST IFN, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_145047-63 Dettaglio
- Opposite effects of murine interferons on erythroid differentiation of Friend cells, AFFABRIS, ELISABETTA, , 1988Link identifier #identifier_person_122307-64 Dettaglio
- Effect of mouse interferon alpha/beta on the expression of H-2 (class I) antigens and on the levels of 2'-5' oligoadenylate synthetase activity in interferon-sensitive and interferon-resistant Friend leukemia cell tumors in mice., AFFABRIS, ELISABETTA, , 1987Link identifier #identifier_person_42130-65 Dettaglio
- MOLECULAR MECHANISMS OF ACTION OF INTERFERONS IN THE FRIEND VIRUS-INDUCED LEUKEMIA-CELL SYSTEM, AFFABRIS, ELISABETTA, , 1987Link identifier #identifier_person_66376-66 Dettaglio
- 2',5'-oligoadenylate synthetase-uninducible alpha, beta interferon-resistant Friend cells develop an antiviral state when permeabilized with lysolecithin and treated with 2',5'- oligoadenylate oligomers, AFFABRIS, ELISABETTA, , 1986Link identifier #identifier_person_109094-67 Dettaglio
- Establishment of the antiviral state in alpha, beta interferon-resistant Friend cells treated with gamma interferon: induction of 67K protein kinase activity in absence of detectable 2-5A synthetase, AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_175703-68 Dettaglio
- Subcellular distribution of 2'-5'-oligoadenylate synthetase in differentiating Friend leukemia cells, AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_38405-69 Dettaglio
- The role of two interferon-induced enzymatic activities in erythroid differentiation of Friend cells., AFFABRIS, ELISABETTA, , 1985Link identifier #identifier_person_189384-70 Dettaglio
- Role of interferon and 2'-5'-olygoadenylate synthetase in erythroid differentiation of Friend leukemia cells, AFFABRIS, ELISABETTA, , 1984Link identifier #identifier_person_4307-71 Dettaglio
- 2-5A synthetase activity does not increase in interferon-resistent Friend leukemia cell variants treated with alpha/beta interferon despite the presence of high-affinity interferon receptor sites, AFFABRIS, ELISABETTA, , 1983Link identifier #identifier_person_71198-72 Dettaglio
- Isolation of interferon-resistant variants of Friend erythroleukemia cells: effects of interferon and ouabain, AFFABRIS, ELISABETTA, , 1982Link identifier #identifier_person_90820-73 Dettaglio
- Modulation of erythroid differentiation induced by DMSO in Friend cells treated with interferon: a clonal analysis, AFFABRIS, ELISABETTA, , 1982Link identifier #identifier_person_140222-74 Dettaglio
- Interactions of interferon with in vitro model systems involved in hematopoietic cell differentiation., AFFABRIS, ELISABETTA, , 1980Link identifier #identifier_person_145119-75 Dettaglio
- Erythroid differentiation of Friend erythroleukemia cells: a "variant" cell line endowed with an early expression of erythroid markers., AFFABRIS, ELISABETTA, , 1978Link identifier #identifier_person_34431-76 Dettaglio
Libro
- Link identifier #identifier_person_8002-77Dettaglio
Contributo in volume e atti di convegno
- PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; GALLO, VALENTINA; AFFABRIS, ELISABETTA, HIV-1 Nef Transfer and Intracellular Signalling in Uninfected Cells.(part 1, Chapter 3), vol. unico, pp. 61 78, 2011 Link identifier #identifier_person_108622-78Dettaglio
- AFFABRIS, ELISABETTA, Antiproliferative effect of interferon beta in mucosal and cutaneous Human Papilloma Virus (HPV) - transformed keratinocytes., CYTOKINE, issn 1043-4666, vol. 43, pp. 330 330, 2008 Link identifier #identifier_person_11784-79Dettaglio
- PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; LEONE, STEFANO; AFFABRIS, ELISABETTA, Recombinant myristoylated HIV-1 Nef protein is able to enter human primary macrophages and monocitic cell line THP-1 activating signal transduction events through a IRAK1 degradation – independent mechanism., 2008 Link identifier #identifier_person_75697-80Dettaglio
- MANGINO, GIORGIO; PERCARIO, ZULEMA ANTONIA; LEONE, STEFANO; LAURO, GIULIANA MARIA; AFFABRIS, ELISABETTA, Recombinant Nef protein induces inflammatory response and upregulation of inducible nitric oxide synthase expression in the murine microglial cell line BV-2., 2008 Link identifier #identifier_person_105504-81Dettaglio
- PERCARIO, ZULEMA ANTONIA; MANGINO, GIORGIO; AFFABRIS, ELISABETTA, The production of interferon-ß induced by HIV-1 Nef treatment of primary human monocyte-derived macrophages requires the PI3K/Akt pathway., 2008 Link identifier #identifier_person_194979-82Dettaglio
- AFFABRIS, ELISABETTA, Virus-cell interactions in Human Immunodeficiency Virus infection: recent advances in viral accessory proteins function., 2008 Link identifier #identifier_person_160225-83Dettaglio
- AFFABRIS, ELISABETTA, In vitro treatment of human monocyte-derived macrophages with HIV-1 protein Nef activates cellular signaling pathways leading to type I Interferon production, vol. Unico, pp. 105 111, 2006 Link identifier #identifier_person_66079-84Dettaglio