Morphological and mechanical properties of biological matter at the nanoscale

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The research aim at investigating the relationship linking morphology and mechanical properties to metabolism and fitness in certain bacterial strain of particular interest for their role in spreading nosocomial infetions, such e.g. Acinetobacter Baumannii.
To this purpose the research relies on a suite of different experimental techniques (AFM-based quantitative nanomechanical mapping, SEM, µRaman) to investigate the impact of different stress, such dehydration,  on the shape and conditions of the outer cell membranes. The bacterial physical properties are then correlated to their fitness, as obtained by e.g. their  clonogenic capability.

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  • Università Federico II, Napoli
Link identifier #identifier__52711-15Link identifier #identifier__110706-16Link identifier #identifier__39010-17
Francesca Vitalini 21 June 2021