Main goals of the course are:
i) to provide an overview of the activities of a clinical laboratory looking at the organizational context and current business;
ii) to illustrate the various stages which are at the basis of main analytical methods, either molecular or biochemical, used in biomedical laboratories for modern diagnostic purposes;
iii) to provide the key of interpretation for the obtained results from a pathophysiological point of view.
To promote a critical approach towards laboratory diagnosis.
i) to provide an overview of the activities of a clinical laboratory looking at the organizational context and current business;
ii) to illustrate the various stages which are at the basis of main analytical methods, either molecular or biochemical, used in biomedical laboratories for modern diagnostic purposes;
iii) to provide the key of interpretation for the obtained results from a pathophysiological point of view.
To promote a critical approach towards laboratory diagnosis.
scheda docente
materiale didattico
Ciaccio. 2021. TRATTATO DI BIOCHIMICA CLINICA E MEDICINA DI LABORATORIO. 1 Ed. Edises Università.
M.L. Turgeon. 2020. MEDICINA NEL LABORATORIO. GLI ESAMI: QUANDO, COME E PERCHE’. 1 Ed. Edra.
Antonozzi, Gulletta. 2019. MEDICINA DI LABORATORIO. LOGICA E PATOLOGIA CLINICA. 3 Ed. Piccin.
Laposata. 2020. MEDICINA DI LABORATORIO. LA DIAGNOSI DI MALATTIA NEL LABORATORIO CLINICO. 2 Ed. Piccin.
Mutuazione: 20401653 BIOCHIMICA E BIOLOGIA MOLECOLARE CLINICA in Biologia Molecolare, Cellulare e della Salute LM-6 R N0 DI MASI ALESSANDRA
Programma
The role of laboratory medicine in the clinical context. The pre-analytical phase. Patient-related variability. Sample-related variability. Enzymatic determinations and their use. Protein diagnostics. Biomarkers of nutritional status. Liver. Dyslipidemia. Hematological diagnostics. Immunohematology. Hemostasis. Thrombophilia. Kidney. Chemical-physical and morphological examination of urine. Blood gas analysis. Cardiac biomarkers. Endocrine system. Diabetes mellitus. Metabolic syndrome. Autoimmune diseases. Allergic diseases. Bone remodeling. Clinical molecular biology. Inflammation biomarkers. Sepsis biomarkers.Testi Adottati
Ciaccio, Lippi. 2020. BIOCHIMICA CLINICA E MEDICINA DI LABORATORIO. 3 Ed. Edises Università.Ciaccio. 2021. TRATTATO DI BIOCHIMICA CLINICA E MEDICINA DI LABORATORIO. 1 Ed. Edises Università.
M.L. Turgeon. 2020. MEDICINA NEL LABORATORIO. GLI ESAMI: QUANDO, COME E PERCHE’. 1 Ed. Edra.
Antonozzi, Gulletta. 2019. MEDICINA DI LABORATORIO. LOGICA E PATOLOGIA CLINICA. 3 Ed. Piccin.
Laposata. 2020. MEDICINA DI LABORATORIO. LA DIAGNOSI DI MALATTIA NEL LABORATORIO CLINICO. 2 Ed. Piccin.
Modalità Frequenza
Optional but strongly recommendedModalità Valutazione
During the semester in which the course is taught, it will be possible to take a midterm written exam approximately halfway through the semester and at the end of the semester. The midterm exam, lasting two hours, will consist of three open-ended questions and 10 multiple-choice questions. The final grade will be based on the average of the grades obtained in the two midterm exams. If a student has not taken one of the two midterm exams or wishes to improve the grade obtained in one of them, they may take the oral exam on the dates set for the parts of the program covered by the modules. Students who do not wish to take the midterm exams during the semester may take the oral exam directly on the dates set for the exams. The final grade will be based on the following parameters: a) Appropriateness, correctness, and consistency of the knowledge and skills acquired; b) Appropriate use of the specific language of the discipline; c) Expressive ability; d) Logical ability; e) Ability to synthesize; f) Ability to connect different topics. Consequently, the assessment may be: a) Sufficient (18 to 20/30) b) Fair (21 to 23) c) Good (24 to 26) d) Very good (27 to 29) e) Excellent (30) Honors are awarded to candidates who are clearly above average and whose any limitations in terms of knowledge, expression, concepts, or logic are, on the whole, completely irrelevant.